Daniel Belsky, PhD, Associate Professor of Epidemiology from the Columbia Aging Center, tested the hypothesis that a healthy diet protects against dementia by slowing down the body’s overall pace of biological ageing.
The researchers used data from the second generation of the Framingham Heart Study, the Offspring Cohort. Originating in 1971, participants in the latter were 60 years of age or older, were free of dementia, and also had available dietary, epigenetic, and follow-up data.
The cohort was followed up in nine examinations every 4-7 years. At each follow-up visit, data collection included a physical examination, lifestylerelated questionnaires, blood sampling, and starting in 1991, neurocognitive testing.
Of 1,644 participants included in the analyses, 140 of the participants developed dementia. To measure the pace of ageing, the researchers used an epigenetic…