1451
Isabella is born to John II of Castile and his wife Isabella of Portugal. Henry, John’s son from his first marriage, is his heir.
1454
After John II’s death, Henry becomes king. A weak ruler, he remains childless until 1462 when his daughter, Joanna, will be born.
1468
Rebellious nobles support Isabella’s claim to the throne. To hold power, Henry is forced to name her his heir over his daughter.
1469
Secretly marrying Ferdinand of Aragon, Isabella defies Henry, who had hoped to marry her to the Portuguese king.
1470
Isabella’s first child, a girl also named Isabella, is born. She will have four more children: John, Joanna, Maria, and Catherine.
1474
Henry IV dies, and soon after, Isabella proclaims herself queen of Castile. Her niece, Joanna, also claims…